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August 31, 2010
An IV for the RCT: using instrumental variables to adjust for treatment contamination in randomised controlled trials
Sussman, JB, Hayward, RA. An IV for the RCT: using instrumental variables to adjust for treatment contamination in randomised controlled trials. BMJ 2010;340:c2073.
Our own Dr. Sussman writes:
"In this article, we describe a simple yet rarely used analytical technique, the "contamination adjusted intention to treat analysis," which complements the intention to treat approach by producing a better estimate of the benefits and harms of receiving a treatment. This method uses the statistical technique of instrumental variable analysis to address contamination."
I'll find a link and post it here...
Posted by rbrent at August 31, 2010 05:38 PM