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June 30, 2006
New Articles from UM SoD Faculty: June 06, part 5
Jung Y. Wang J. Schneider A. Sun YX. Koh-Paige AJ. Osman NI. McCauley LK. Taichman RS.
Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
Bone. 38(4):497-508, 2006 Apr.
PMID: 16337237
Mantellini MG. Botero T. Yaman P. Dennison JB. Hanks CT. Nor JE.
Adhesive resin and the hydrophilic monomer HEMA induce VEGF expression on dental pulp cells and macrophages.
Dental Materials. 22(5):434-40, 2006 May.
PMID: 16182358
Pinsky MS. Song W. Dong Z. Warner K. Zeitlin B. Karl E. Hall DE. Nor JE.
Activation of iCaspase-9 in neovessels inhibits oral tumor progression.
Journal of Dental Research. 85(5):436-41, 2006 May.
PMID: 16632757
Sarment DP. Cooke JW. Miller SE. Jin Q. McGuire MK. Kao RT. McClain PK. McAllister BS. Lynch SE. Giannobile WV.
Effect of rhPDGF-BB on bone turnover during periodontal repair.
Journal of Clinical Periodontology. 33(2):135-40, 2006 Feb.
PMID: 16441739
Posted by pfa at 08:47 AM | Comments (0)
New in PubMed: Related Articles Enhanced
Are you one of the many people using PubMed as your preferred source for Medline searching? Patrons who choose PubMed over OVID for MEDLINE access have told me there are two favorite features of PubMed that contribute to this choice. One is the "Single Citation Matcher" and the other is the "Related Articles" option. Well, the "Related Articles" option has just been improved.
Previously, you would do a search, and then select an article you wanted to look at, such as this one by Laurie McCauley.
McCauley LK, Tozum TF, Kozloff KM, Koh-Paige AJ, Chen C, Demashkieh M, Cronovich H, Richard V, Keller ET, Rosol TJ, Goldstein SA.
Transgenic models of metabolic bone disease: impact of estrogen receptor deficiency on skeletal metabolism.
Connect Tissue Res. 2003;44 Suppl 1:250-63.
PMID: 12952206
In the listing of articles, beside the author names, you would see the words "Related Articles, Links" as active links. If you clicked on "Related Articles", you would then receive a new list of articles that begins with the article you selected. This list is usually very long. For example, today, using the McCauley article above as the jumping-off point, there are 646 related articles.
So, what has changed? Let's say you don't want 646 related articles, at least not to start with. You have an article of interest, perhaps you might think of it as a target article. From the list, you would normally click on the authors for the target article, and this will put you in to the Abstract Display (including citation, PMID, contact information and abstract). Above the article citation, is a menu with a variety of options to customize your display. There is a new option in the "Display" menu -- "AbstractPlus". With this choice, the display gives you a blend of the "Abstract" display and the "Related Articles" -- you will see the top 5 related articles displayed beside the abstract. For the McCauley article that is our target article, these are shown like this:
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Related Links
Effects of sex steroid receptor specificity in the regulation of skeletal metabolism. [Calcif Tissue Int. 2004] PMID: 15037970
Estrogen receptor specificity in the regulation of the skeleton in female mice. [J Endocrinol. 2001] PMID: 11691642
Female estrogen receptor beta-/- mice are partially protected against age-related trabecular bone loss. [J Bone Miner Res. 2001] PMID: 11499861
Effect of osteoblast-targeted expression of bcl-2 in bone: differential response in male and female mice. [J Bone Miner Res. 2005] PMID: 16007339
Estrogen responsiveness of bone formation in vitro and altered bone phenotype in aged estrogen receptor-alpha-deficient male and female mice. [Eur J Endocrinol. 2005] PMID: 15745940
See all Related Articles...
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A nice feature! Try it out ...
Posted by pfa at 08:16 AM | Comments (0)
June 26, 2006
NIH on Pain and Pain Research
Findings from the NIH Pain Consortium's first symposium are now beginning to be made available to the general public. This month's consumer health newsletter from NIH (NewsInHealth) highlights the idea that a positive outlook can significantly help in pain management. Please see the links below for additional information about the Pain Consortium, the symposium (which is supposed to be made available as a webcast soon), and more.
NIH: NewsInHealth (June 2006): Ignore the Pain? Innovative Pain Management Ideas:
http://newsinhealth.nih.gov/2006/June/docs/01features_01.htm
NIH: Pain Consortium: http://painconsortium.nih.gov/
NIH Pain Consortium: First Annual Symposium, Advances in Pain Research, April 17-18, 2006: Highlights in Pain Research - Genetics, Neuronal & Glial Mechanisms, Imaging, Cognitive & Emotional Aspects, Headache, Cancer Pain, Novel Therapies, Junior Investigators:
http://conferences.masimax.com/painconsortium/agenda.cfm
NIH: Pain Consortium: NIH Pain Research: Pain Information Index: http://painconsortium.nih.gov/pain_index.html
NIH: Pain Consortium: Interactive Textbook of Pain and Symptom Research: http://painconsortium.nih.gov/symptomresearch/index.html
NIH: Pain Consortium: Pain Intensity Scales: http://painconsortium.nih.gov/pain_scales/index.html
Posted by pfa at 01:59 PM | Comments (0)
June 22, 2006
New Articles from UM SoD Faculty: June 06, part 4
Hill E. Boontheekul T. Mooney DJ.
Regulating activation of transplanted cells controls tissue regeneration.
Proceedings of the National Academy of Sciences of the United States of America. 103(8):2494-9, 2006 Feb 21.
PMID: 16477029
Magliocca KR. Kessel NC. Cortright GW.
Transient diplopia following maxillary local anesthetic injection.
Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics. 101(6):730-3, 2006 Jun.
PMID: 16731391
Sedgley C. Nagel A. Dahlen G. Reit C. Molander A.
Real-time quantitative polymerase chain reaction and culture analyses of enterococcus faecalis in root canals.
Journal of Endodontics. 32(3):173-7, 2006 Mar.
PMID: 16500220
Posted by pfa at 02:59 PM | Comments (0)
June 21, 2006
A Return to the Focal Infection Theory? Dentistry and Systemic Diseases
While preparing our forthcoming exhibit on the history of dentistry in Michigan, I stumbled across a clever little rhyme that was presented in the entertainment column of the MDA Journal.
There was a little man and he had a little fang
And a billion or so of strepto bugs were in it.
A dentist of renown said I'll put thereon a crown,
For I need all the money there is in it.
Thereupon he made a start; The bugs traveled to the heart,
Of the little man, I really hate to sing it,
For soon there was no little fang, There was no little man,
The tale's too sad, I can't go on, Oh why did I begin it?
Buzzer, A. [pseud.?] "Saydiograms." Michigan State Dental Society Bulletin (June 1924) 6:28.
With that in mind, I thought it would be interesting to highlight a few of this year's articles on the relationship between periodontal disease and various systemic diseases, a recently resurfacing concept very similar to the earlier discredited focal infection theory which, in its heyday, gave rise to the rhyme above.
Each of the articles below was published this year, and either describes a systemic disease as a complication of periodontal diseases or describes periodontal disease as a risk factor for the systemic disease. The Shetty article proposes a mechanism for this -- that the periodontal infection may contribute to immunosuppression.
Al-Zahrani MS. Kayal RA. Bissada NF. Periodontitis and cardiovascular disease: a review of shared risk factors and new findings supporting a causality hypothesis. Quintessence International. 37(1):11-8, 2006 Jan.
UI: 16429698
D'Aiuto F. Parkar M. Nibali L. Suvan J. Lessem J. Tonetti MS. Periodontal infections cause changes in traditional and novel cardiovascular risk factors: results from a randomized controlled clinical trial. American Heart Journal. 151(5):977-84, 2006 May.
UI: 16644317
Moss KL. Mauriello S. Ruvo AT. Offenbacher S. White RP Jr. Beck JD. Reliability of third molar probing measures and the systemic impact of third molar periodontal pathology. Journal of Oral & Maxillofacial Surgery. 64(4):652-8, 2006 Apr.
UI: 16546645
Schara R. Medvescek M. Skaleric U. Periodontal disease and diabetes metabolic control: a full-mouth disinfection approach. Journal of the International Academy of Periodontology. 8(2):61-6, 2006 Apr.
UI: 16623181
Shetty K. The role of salivary cytokines in the etiology and progression of periodontal disease. General Dentistry. 54(2):140-3; quiz 144, 2006 Mar-Apr.
UI: 16689073
Xiong X. Buekens P. Fraser WD. Beck J. Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG: An International Journal of Obstetrics & Gynaecology. 113(2):135-43, 2006 Feb.
UI: 16411989
Posted by pfa at 04:27 PM | Comments (0)
June 15, 2006
New Articles from UM SoD Faculty: June 06, part 3
Hu JC. Yamakoshi Y. Yamakoshi F. Krebsbach PH. Simmer JP.
Proteomics and genetics of dental enamel.
Cells Tissues Organs. 181(3-4):219-31, 2005.
PMID: 16612087
Melegari KK. Botero TM. Holland GR. Prostaglandin E production and viability of cells cultured in contact with freshly mixed endodontic materials. International Endodontic Journal. 39(5):357-62, 2006 May.
PMID: 16640633
Ramseier CA. Christen A. McGowan J. McCartan B. Minenna L. Ohrn K. Walter C. Tobacco use prevention and cessation in dental and dental hygiene undergraduate education. Oral Health & Preventive Dentistry. 4(1):49-60, 2006.
PMID: 16683397
Smith YR. Stohler CS. Nichols TE. Bueller JA. Koeppe RA. Zubieta JK. Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in women. Journal of Neuroscience. 26(21):5777-85, 2006 May 24.
PMID: 16723535
Posted by pfa at 07:47 PM | Comments (0)
June 14, 2006
More Cultural Competency Resources
Training healthcare professionals to work effectively with all types of patients represented in their practice is widely acknowledged to be a good thing. Likewise, recruiting diverse types of practitioners is another route toward providing equitable care to all. Here are some resources of note to support these goals.
AAMC: Tool for Assessing Cultural Competence Training (TACCT):
http://www.aamc.org/meded/tacct/start.htm
Also: http://www.aamc.org/diversity/initiatives.htm
British Medical Association: Equality and diversity: Improving the working lives of doctors, April 2006: http://www.bma.org.uk/ap.nsf/Content/equalitydiversity
California Department of Health Services: Office of Multicultural Health: http://www.dhs.ca.gov/director/omh/
Colorado Foundation for Medical Care (CFMC): Physician Office's Guide to Culturally Competent Care: http://www.cfmc.org/office/office_cultural-competency.htm
Cross Cultural Health Care Program: http://www.xculture.org/
Dental Pipeline Projects: Community-Based Dental Education: Cultural Competency Resources: http://www.dentalpipeline.org/home/697/25001/25067
Diversity Health institute (Australia): http://www.dhi.gov.au/
DiversityRx: http://www.diversityrx.org/
Michigan Surgeon General’s Prescription for a Healthier Michigan [PDF 304KB]: http://www.michigan.gov/documents/mirx5404_90138_7.pdf
National Center for Cultural Healing: http://www.culturalhealing.com/
University of Michigan Health System: Program for Multicultural Health: Cultural Competency Division: http://www.med.umich.edu/multicultural/ccp/index.htm
Also: Cultural Competency Web Resources (which includes a section specifically on dentistry):
http://www.med.umich.edu/multicultural/ccp/culcomp.htm
US: Office of Minority Health: http://www.omhrc.gov/
US: HRSA: Bureau of Health Professions: Diversity:
http://bhpr.hrsa.gov/diversity/
Posted by pfa at 10:11 AM | Comments (0)
June 13, 2006
A Dentist's POV in the Iraqi War
There is an Iraqi dentist who goes by "Zeyad" blogging for the New York Times about his personal experiences of the Iraqi war.
New York Times: Select: Day to Day in Iraq: http://daytodayiniraq.blogs.nytimes.com/
"Zeyad is a 27-year-old dentist in Baghdad and the author of the blog, Healing Iraq. He was born in Baghdad and spent most of the first eight years of his life in England. He returned to Iraq with his family in 1986 and has been based there ever since. He has been posting on his blog since October 2003."
Here is the link to his personal blog.
Healing Iraq (Daily news and comments on the situation in post Saddam Iraq by an Iraqi dentist): http://healingiraq.blogspot.com/
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EXCERPT:
As my cousin led me across the street back home, I burst uncontrollably into tears. “How could you go out in your shorts?” he was saying, almost to himself. “Are you out of your mind? Haven’t you heard that they banned shorts?” ...
“Them?” I yelled back. “How long are we going to cower in fear and wait for them to get to us too? How long until we’re next in the line?”
“Yes, living here is like waiting in a damn line to get killed,” he said. “Either you learn to live with it, or you leave. Period.”
The gravity of what I did struck me the next day. I had gone out in shorts – explicitly banned by Islamists, insurgents, the “resistance,” or whoever, in our area – in front of all to check on a Shiite friend whom they deemed as an enemy and worthy of execution, for whatever reasons.
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Posted by pfa at 02:40 PM | Comments (0)
Medical Identity Theft
The World Privacy Forum has released a report on the problem of medical identity theft.
Medical Identity Theft: The Information Crime that Can Kill You (Released May 3, 2006), by Pam Dixon and Robert Gellman:
http://www.worldprivacyforum.org/medicalidentitytheft.html
With financial identity theft, you find that someone has stolen your identity to make use of your financial resources and credit. With medical identity theft, this may happen -- the thief may use your insurance or other resources, and you may also find that the identity thief has changed your medical records to include fictitious information. Examples included changing the bloodtype on record and adding psychiatric diagnoses.
Recommendations for personal protection include frequently requesting copies of your files, just as you should request copies of your credit report, and closely reviewing all communications from your insurance company. Practitioners need to be aware of this in order to question apparent inconsistencies between the record and the patient's reporting.
Posted by pfa at 11:47 AM | Comments (0)
June 10, 2006
Dental Research in the News
Remember JAMA's amalgam articles from April? Consumer Reports has just released their update on the safety of mercury for children.
Consumer Reports, June 2006: Tooth-filling safety for kids; Some reassurance about dental amalgams, but more is needed: http://www.consumerreports.org/cro/babies-kids/news/tooth-filling-safety-for-kids-6-06/overview/0606_tooth-filling-safety-for-kids.htm
Meanwhile, another dental research study on how dentists incorporate new guidelines in practice has been getting less positive attention.
Bonetti D.
Guideline improved dentists' knowledge but not their clinical decision-making skills: Is a clinical practice guideline on the management of asymptomatic impacted lower third molars effective in changing practice?
Evid Based Dent. 2006;7(1):8.
While not cutting-edge, Horace Wells and William Morton, both praised for their contributions to the discovery of dental anesthesia, are highlighted in a UK article about scientific researchers who experimented on themselves.
TimesOnline (June 10, 2006): Doctors who had a taste of their own medicine (Many of the most important medical advances have resulted from scientists who experimented on themselves. Whether foolhardy or selfless, Wendy Moore salutes these maverick medics): http://www.timesonline.co.uk/article/0,,8123-2217159,00.html
Posted by pfa at 10:31 AM | Comments (0)
June 09, 2006
ISI Web Of Knowledge Update
The Web of Knowledge / Web of Science resource from ISI has again dramatically expanded their historical searching capability. A few years ago, they shifted their earliest date to 1945, and we were impressed with that. Now they have shifted it back to 1900, an absolutely astonishing feat. In the database you would select for searching:
Science Citation Index Expanded (SCI-EXPANDED)--1900-present
This will dramatically improve access to formative research, and is a very exciting resource for those tracking the intellectual heritage of their research concepts. Obviously, this is an absolute must for scientific historians of any sort.
Posted by pfa at 09:38 AM | Comments (0)
June 08, 2006
How's that Headache? Seen Your Dentist Lately?
June 4-10th is National Headache Awareness Week for 2006. NHAW is sponsored by the National Headache Foundation.
National Headache Foundation: http://www.headaches.org/
"This year's theme, Headache Relief: 12 Tips for a Headache Free Year conveys the importance of managing headaches at home, work and play."
National Headache Awareness Week: http://www.headaches.org/consumer/NHAW/NHAW06.html
Along those lines, you might want to be aware of a new online headache assessment tool from the University of Medicine and Dentistry of New Jersey.
HeadacheConsult: http://www.headacheconsult.com/
You might be interested in these other resources on dentists, dentistry and headaches. These range from those for patients to information for practitioners and about new inventions for headache treatment coming out of dental research.
American Academy of Head, Neck and Facial Pain (AAHNFP) / American Academy of Craniofacial Pain (AACFP): Headaches and Dental Health: http://www.aacfp.org/headaches.html
Army Medicine: Dental-Related Headaches, by Capt. Mark Vance: http://www.armymedicine.army.mil/hc/healthtips/02/200411dentalheadaches.cfm
Chicago Dental Society: Dental device grabs migraine Rx headlines, July 1, 2005:
http://www.cds.org/for_your_practice/professional_news_articles/articles_item_detail.wu4?categ=practice&articleid=21c69b05
While I was finding these resources for this special week of headache information, I also discovered that last week was "I Love My Dentist Day". Now, how did I miss that?
June 2 – I Love My Dentist Day: http://www.edhelper.com/DailyThemes_875.html
Posted by pfa at 04:24 PM | Comments (0)
Clinical Researchers In the News
I've been having trouble with the mBlog software killing off my entries during editing, so please pardon me if there are several sent at once while I try to catch up.
I'd like to bring to your attention the following report of the AAMC in which they call for schools to specifically work to create the next generation of clinical researchers in their educational process.
Promoting Translational and Clinical Science: The Critical Role of Medical Schools and Teaching Hospitals (Report of the AAMC's Task Force II on Clinical Research) May 2006 [62 Pages, PDF 1 MB]: https://services.aamc.org/Publications/index.cfm?fuseaction=Product.displayForm&prd_id=150&prv_id=176
Next, did you see the International Clinical Trials Day? This was last month, so I am sorry to be late bringing this to your attention. A good idea, and I hope it receives broader attention next year. For the record, mark your calendars for May 19th.
European Clinical Research Infrastructures Network (ACRIN): International Clinical Trials' Day: http://www.ecrin.org/ecrin_files/news.php?level=1
Also of potential interest, the American Academy of Microbiology has just issued a new report on "good bugs" -- "how beneficial microbes could represent the future of medicine, with the potential to treat a variety of diseases in humans and animals from diarrhea and eczema to gum disease and autoimmune disorders."
American Academy of Microbiology (AAM) : Critical Issues Colloquia Reports: "Probiotic Microbes: The Scientific Basis," June 2006: http://www.asm.org/Academy/index.asp?bid=43351
Last but far from least for today's entry, the Public Library of Sciences has released a new journal title in collaboration with the AAMC on clinical research.
PLoS Clinical Trials: http://clinicaltrials.plosjournals.org/
Posted by pfa at 03:38 PM | Comments (0)
New Articles from UM SoD Faculty: June 06, part 2
Patel AM. Richards PS. Wang HL. Inglehart MR.
Surgical or non-surgical periodontal treatment: factors affecting patient decision making.
Journal of Periodontology. 77(4):678-83, 2006 Apr.
PMID: 16584350
Tsao YP. Neiva R. Al-Shammari K. Oh TJ. Wang HL.
Factors influencing treatment outcomes in mandibular Class II furcation defects.
Journal of Periodontology. 77(4):641-6, 2006 Apr.
PMID: 16584345
Posted by pfa at 03:32 PM | Comments (0)
June 01, 2006
New Articles from UM SoD Faculty: June 06, part 1
Geran RG. McNamara JA Jr. Baccetti T. Franchi L. Shapiro LM. A prospective long-term study on the effects of rapid maxillary expansion in the early mixed dentition. American Journal of Orthodontics & Dentofacial Orthopedics. 129(5):631-40, 2006 May. PMID: 16679203
Ramseier CA. Abramson ZR. Jin Q. Giannobile WV. Gene therapeutics for periodontal regenerative medicine. Dental Clinics of North America. 50(2):245-63, ix, 2006 Apr. PMID: 16530061
Wang HL. Boyapati L. "PASS" principles for predictable bone regeneration. Implant Dentistry. 15(1):8-17, 2006 Mar. PMID: 16569956
Posted by pfa at 10:27 AM | Comments (0)